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Improved survival and overt “dystonic” symptoms in a torsinA hypofunction mouse model

DYT1 dystonia is an inherited movement disorder without obvious neurodegeneration. Multiple mutant mouse models exhibit motor deficits without overt “dystonic” symptoms and neurodegeneration. However, some mouse models do. Among the later models, the N-CKO mouse model, which has a heterozygous Tor1a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Behav Brain Res
Egile Nagusiak: Yokoi, Fumiaki, Jiang, Fangfang, Dexter, Kelly, Salvato, Bryan, Li, Yuqing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140139/
https://ncbi.nlm.nih.gov/pubmed/31891745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2019.112451
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