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Improved survival and overt “dystonic” symptoms in a torsinA hypofunction mouse model

DYT1 dystonia is an inherited movement disorder without obvious neurodegeneration. Multiple mutant mouse models exhibit motor deficits without overt “dystonic” symptoms and neurodegeneration. However, some mouse models do. Among the later models, the N-CKO mouse model, which has a heterozygous Tor1a...

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Bibliografski detalji
Izdano u:Behav Brain Res
Glavni autori: Yokoi, Fumiaki, Jiang, Fangfang, Dexter, Kelly, Salvato, Bryan, Li, Yuqing
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140139/
https://ncbi.nlm.nih.gov/pubmed/31891745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2019.112451
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