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Improved survival and overt “dystonic” symptoms in a torsinA hypofunction mouse model

DYT1 dystonia is an inherited movement disorder without obvious neurodegeneration. Multiple mutant mouse models exhibit motor deficits without overt “dystonic” symptoms and neurodegeneration. However, some mouse models do. Among the later models, the N-CKO mouse model, which has a heterozygous Tor1a...

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Podrobná bibliografie
Vydáno v:Behav Brain Res
Hlavní autoři: Yokoi, Fumiaki, Jiang, Fangfang, Dexter, Kelly, Salvato, Bryan, Li, Yuqing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140139/
https://ncbi.nlm.nih.gov/pubmed/31891745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2019.112451
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