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Improved survival and overt “dystonic” symptoms in a torsinA hypofunction mouse model

DYT1 dystonia is an inherited movement disorder without obvious neurodegeneration. Multiple mutant mouse models exhibit motor deficits without overt “dystonic” symptoms and neurodegeneration. However, some mouse models do. Among the later models, the N-CKO mouse model, which has a heterozygous Tor1a...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Yokoi, Fumiaki, Jiang, Fangfang, Dexter, Kelly, Salvato, Bryan, Li, Yuqing
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140139/
https://ncbi.nlm.nih.gov/pubmed/31891745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2019.112451
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