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Improved survival and overt “dystonic” symptoms in a torsinA hypofunction mouse model
DYT1 dystonia is an inherited movement disorder without obvious neurodegeneration. Multiple mutant mouse models exhibit motor deficits without overt “dystonic” symptoms and neurodegeneration. However, some mouse models do. Among the later models, the N-CKO mouse model, which has a heterozygous Tor1a...
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| Publicado en: | Behav Brain Res |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7140139/ https://ncbi.nlm.nih.gov/pubmed/31891745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2019.112451 |
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