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Global DNA Hypomethylation in Epithelial Ovarian Cancer: Passive Demethylation and Association with Genomic Instability

A hallmark of human cancer is global DNA hypomethylation (GDHO), but the mechanisms accounting for this defect and its pathological consequences have not been investigated in human epithelial ovarian cancer (EOC). In EOC, GDHO was associated with advanced disease and reduced overall and disease-free...

詳細記述

保存先:
書誌詳細
出版年:Cancers (Basel)
主要な著者: Zhang, Wa, Klinkebiel, David, Barger, Carter J., Pandey, Sanjit, Guda, Chittibabu, Miller, Austin, Akers, Stacey N., Odunsi, Kunle, Karpf, Adam R.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140107/
https://ncbi.nlm.nih.gov/pubmed/32213861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030764
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