PRAME expression and promoter hypomethylation in epithelial ovarian cancer

PRAME is a cancer-testis antigen (CTA) and potential immuno-therapeutic target, but has not been well-studied in epithelial ovarian cancer (EOC) or its high grade serous (HGSC) subtype. Compared to normal ovary, PRAME expression was significantly increased most EOC, regardless of stage and grade. In...

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Udgivet i:Oncotarget
Main Authors: Zhang, Wa, Barger, Carter J., Eng, Kevin H., Klinkebiel, David, Link, Petra A., Omilian, Angela, Bshara, Wiam, Odunsi, Kunle, Karpf, Adam R.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216727/
https://ncbi.nlm.nih.gov/pubmed/27322684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9977
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