DNA hypomethylation-mediated activation of Cancer/Testis Antigen 45 (CT45) genes is associated with disease progression and reduced survival in epithelial ovarian cancer

Epithelial ovarian cancer (EOC) is a highly lethal malignancy due to a lack of early detection approaches coupled with poor outcomes for patients with clinically advanced disease. Cancer-testis (CT) or cancer-germline genes encode antigens known to generate spontaneous anti-tumor immunity in cancer...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Zhang, Wa, Barger, Carter J, Link, Petra A, Mhawech-Fauceglia, Paulette, Miller, Austin, Akers, Stacey N, Odunsi, Kunle, Karpf, Adam R
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622579/
https://ncbi.nlm.nih.gov/pubmed/26098711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1062206
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