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Global DNA Hypomethylation in Epithelial Ovarian Cancer: Passive Demethylation and Association with Genomic Instability

A hallmark of human cancer is global DNA hypomethylation (GDHO), but the mechanisms accounting for this defect and its pathological consequences have not been investigated in human epithelial ovarian cancer (EOC). In EOC, GDHO was associated with advanced disease and reduced overall and disease-free...

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Podrobná bibliografie
Vydáno v:Cancers (Basel)
Hlavní autoři: Zhang, Wa, Klinkebiel, David, Barger, Carter J., Pandey, Sanjit, Guda, Chittibabu, Miller, Austin, Akers, Stacey N., Odunsi, Kunle, Karpf, Adam R.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140107/
https://ncbi.nlm.nih.gov/pubmed/32213861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030764
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