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Nonsense-Mediated mRNA Decay: Pathologies and the Potential for Novel Therapeutics
Nonsense-mediated messenger RNA (mRNA) decay (NMD) is a surveillance pathway used by cells to control the quality mRNAs and to fine-tune transcript abundance. NMD plays an important role in cell cycle regulation, cell viability, DNA damage response, while also serving as a barrier to virus infection...
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| Published in: | Cancers (Basel) |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7140085/ https://ncbi.nlm.nih.gov/pubmed/32213869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030765 |
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