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Selective degradation of IKKα by autophagy is essential for arsenite-induced cancer cell apoptosis

Two catalytic subunits of the IKK complex, IKKα and IKKβ, trigger NF-κB activation as well as NF-κB-independent signaling events under both physiological and pathological conditions. Here we identified the NF-κB-unrelated cytoprotective function of IKKα in promoting autophagy by triggering p53 trans...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Death Dis
मुख्य लेखकों: Tan, Qixing, Zou, Shuxian, Jin, Rui, Hu, Yongliang, Xu, Huan, Wang, Hongli, Ding, Mengnan, Hu, Meiru, Wei, Changyuan, Song, Lun
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138825/
https://ncbi.nlm.nih.gov/pubmed/32265434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2420-5
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