Ribosomal protein S7 regulates arsenite-induced GADD45α expression by attenuating MDM2-mediated GADD45α ubiquitination and degradation

The stress-responding protein, GADD45α, plays important roles in cell cycle checkpoint, DNA repair and apoptosis. In our recent study, we demonstrate that GADD45α undergoes a dynamic ubiquitination and degradation in vivo, which process can be blocked by the cytotoxic reagent, arsenite, resulting in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gao, Ming, Li, Xiaoguang, Dong, Wen, Jin, Rui, Ma, Hanghang, Yang, Pingxun, Hu, Meiru, Li, Yi, Hao, Yi, Yuan, Shengtao, Huang, Junjian, Song, Lun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664810/
https://ncbi.nlm.nih.gov/pubmed/23563151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt223
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados