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GADD45α inhibition of DNMT1 dependent DNA methylation during homology directed DNA repair
In this work, we examine regulation of DNA methyltransferase 1 (DNMT1) by the DNA damage inducible protein, GADD45α. We used a system to induce homologous recombination (HR) at a unique double-strand DNA break in a GFP reporter in mammalian cells. After HR, the repaired DNA is hypermethylated in rec...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315326/ https://ncbi.nlm.nih.gov/pubmed/22135303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1115 |
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