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The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis

The IκB kinase (IKK) complex is composed of three subunits, IKKα, IKKβ, and IKKγ (NEMO). While IKKα and IKKβ are highly similar catalytic subunits, both capable of IκB phosphorylation in vitro, IKKγ is a regulatory subunit. Previous biochemical and genetic analyses have indicated that despite their...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Zhi-Wei, Chu, Wenming, Hu, Yinling, Delhase, Mireille, Deerinck, Tom, Ellisman, Mark, Johnson, Randall, Karin, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193082/
https://ncbi.nlm.nih.gov/pubmed/10359587
Tagiau: Ychwanegu Tag
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