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The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis

The IκB kinase (IKK) complex is composed of three subunits, IKKα, IKKβ, and IKKγ (NEMO). While IKKα and IKKβ are highly similar catalytic subunits, both capable of IκB phosphorylation in vitro, IKKγ is a regulatory subunit. Previous biochemical and genetic analyses have indicated that despite their...

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Detalhes bibliográficos
Main Authors: Li, Zhi-Wei, Chu, Wenming, Hu, Yinling, Delhase, Mireille, Deerinck, Tom, Ellisman, Mark, Johnson, Randall, Karin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193082/
https://ncbi.nlm.nih.gov/pubmed/10359587
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