IRF-1 mediates the suppressive effects of mTOR inhibition on arterial endothelium

AIMS: Mammalian target of rapamycin (mTOR) inhibitors used in drug-eluting stents (DES) to control restenosis have been found to delay endothelialization and increase incidence of late-stent thrombosis through mechanisms not completely understood. We revealed that mTOR inhibition (mTORi) upregulated...

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Опубликовано в: :J Mol Cell Cardiol
Главные авторы: Peng, Kai, Fan, Xing, Li, Qiannan, Wang, Yiying, Chen, Xiaolin, Xiao, Pingxi, Passerini, Anthony G., Simon, Scott I., Sun, ChongXiu
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138750/
https://ncbi.nlm.nih.gov/pubmed/32087218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2020.02.006
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