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Design of Synthetic shRNAs for Targeting Hepatitis C: A New Approach to Antiviral Therapeutics
Small hairpin RNAs (shRNAs) are widely used as gene silencing tools and typically consist of a duplex stem of 19–29 bp, a loop, and often a dinucleotide overhang at the 3′ end. Like siRNAs, shRNAs show promise as potential therapeutic agents due to their high level of specificity and potency, althou...
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| Publicat a: | From Nucleic Acids Sequences to Molecular Medicine |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7138429/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-27426-8_18 |
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