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Design of Synthetic shRNAs for Targeting Hepatitis C: A New Approach to Antiviral Therapeutics
Small hairpin RNAs (shRNAs) are widely used as gene silencing tools and typically consist of a duplex stem of 19–29 bp, a loop, and often a dinucleotide overhang at the 3′ end. Like siRNAs, shRNAs show promise as potential therapeutic agents due to their high level of specificity and potency, althou...
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| 出版年: | From Nucleic Acids Sequences to Molecular Medicine |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7138429/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-27426-8_18 |
| タグ: |
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