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GABARAPs and LC3s have opposite roles in regulating ULK1 for autophagy induction
ULK1 (unc-51 like autophagy activating kinase 1) is the key mediator of MTORC1 signaling to macroautophagy/autophagy. ULK1 functions as a protein complex by interacting with ATG13, RB1CC1/FIP200, and ATG101. How the ULK1 complex is regulated to trigger autophagy induction remains unclear. In this st...
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| Publicado no: | Autophagy |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7138202/ https://ncbi.nlm.nih.gov/pubmed/31208283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1632620 |
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