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Development of a chimeric model to study and manipulate human microglia in vivo
iPSC-derived microglia offer a powerful tool to study microglial homeostasis and disease-associated inflammatory responses. Yet, microglia are highly sensitive to their environment, exhibiting transcriptomic deficiencies when kept in isolation from the brain. Furthermore, species-specific genetic va...
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| Vydáno v: | Neuron |
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7138101/ https://ncbi.nlm.nih.gov/pubmed/31375314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.07.002 |
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