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Development and validation of a simplified method to generate human microglia from pluripotent stem cells

BACKGROUND: Microglia, the principle immune cells of the brain, play important roles in neuronal development, homeostatic function and neurodegenerative disease. Recent genetic studies have further highlighted the importance of microglia in neurodegeneration with the identification of disease risk p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Neurodegener
Egile Nagusiak: McQuade, Amanda, Coburn, Morgan, Tu, Christina H., Hasselmann, Jonathan, Davtyan, Hayk, Blurton-Jones, Mathew
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303871/
https://ncbi.nlm.nih.gov/pubmed/30577865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0297-x
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