The Critical Role of Toll-Like Receptor (TLR) 4 in Alcoholic Liver Disease Is Independent of the Common TLR Adapter MyD88

The Toll-like receptor 4 (TLR4) that recognizes endotoxin, a trigger of inflammation in alcoholic liver disease (ALD), activates two signaling pathways utilizing different adapter molecules: the common TLR adapter, myeloid differentiation factor 88 (MyD88), or Toll/interleukin immune-response–domain...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Hritz, Istvan, Mandrekar, Pranoti, Velayudham, Arumugam, Catalano, Donna, Dolganiuc, Angela, Kodys, Karen, Kurt-Jones, Evelyn, Szabo, Gyongyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137387/
https://ncbi.nlm.nih.gov/pubmed/18792393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22470
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