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Human binge alcohol intake inhibits TLR4-MyD88 and TLR4-TRIF responses but not TLR3-TRIF pathway: HspA1A and PP1 play selective regulatory roles()
Binge/moderate alcohol suppresses TLR4-MyD88 pro-inflammatory cytokines. However, alcohol effects on TLR-TRIF signaling, especially after in vivo exposure in humans, are unclear. We performed comparative analysis of TLR4-MyD88, TLR4-TRIF and TLR3-TRIF pathways in human monocytes following binge alco...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5860983/ https://ncbi.nlm.nih.gov/pubmed/29445009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600924 |
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