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Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation

Toll-like receptors (TLRs) recognize specific pathogen–associated molecular patterns and initiate innate immune responses through signaling pathways that depend on the adaptor proteins MyD88 (myeloid differentiation marker 88) or TRIF (TIR domain–containing adaptor protein–inducing interferon-β). TL...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Cheng, Zhang, Taylor, Brooks, Ourthiague, Diana R., Hoffmann, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764925/
https://ncbi.nlm.nih.gov/pubmed/26175492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa5208
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