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Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation
Toll-like receptors (TLRs) recognize specific pathogen–associated molecular patterns and initiate innate immune responses through signaling pathways that depend on the adaptor proteins MyD88 (myeloid differentiation marker 88) or TRIF (TIR domain–containing adaptor protein–inducing interferon-β). TL...
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| Udgivet i: | Sci Signal |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6764925/ https://ncbi.nlm.nih.gov/pubmed/26175492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa5208 |
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