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A single bacterial immune evasion strategy dismantles both MyD88 and TRIF signalling pathways downstream of TLR4
During bacterial infections, Toll-like receptor 4 (TLR4) signals through the MyD88-dependent pathway to promote rapid pro-inflammatory responses, but also signals via the TRIF-dependent pathway, which promotes Type-I interferon responses and acts with MyD88 signaling to potentiate inflammatory cytok...
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| Udgivet i: | Cell Host Microbe |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685476/ https://ncbi.nlm.nih.gov/pubmed/26651944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.11.006 |
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