FBXO22 degrades nuclear PTEN to promote tumorigenesis

Nuclear localization of PTEN is essential for its tumor suppressive role, and loss of nuclear PTEN is more prominent than cytoplasmic PTEN in many kinds of cancers. However, nuclear PTEN-specific regulatory mechanisms were rarely reported. Based on the finding that nuclear PTEN is more unstable than...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Ge, Meng-Kai, Zhang, Na, Xia, Li, Zhang, Cheng, Dong, Shuang-Shu, Li, Zhan-Ming, Ji, Yan, Zheng, Min-Hua, Sun, Jing, Chen, Guo-Qiang, Shen, Shao-Ming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136256/
https://ncbi.nlm.nih.gov/pubmed/32249768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15578-1
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller