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FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation
Krüppel-like factor 4 (KLF4, GKLF) is a zinc-finger transcription factor involved in a large variety of cellular processes, including apoptosis, cell cycle progression, as well as stem cell renewal. KLF4 is critical for cell fate decision and has an ambivalent role in tumorigenesis. Emerging data ke...
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| 出版年: | Oncogene |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926769/ https://ncbi.nlm.nih.gov/pubmed/28068319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.479 |
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