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FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation

Krüppel-like factor 4 (KLF4, GKLF) is a zinc-finger transcription factor involved in a large variety of cellular processes, including apoptosis, cell cycle progression, as well as stem cell renewal. KLF4 is critical for cell fate decision and has an ambivalent role in tumorigenesis. Emerging data ke...

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Bibliografische gegevens
Gepubliceerd in:Oncogene
Hoofdauteurs: Zhou, H, Liu, Y, Zhu, R, Ding, F, Wan, Y, Li, Y, Liu, Z
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926769/
https://ncbi.nlm.nih.gov/pubmed/28068319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.479
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