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FBXO32 Targets c-Myc for Proteasomal Degradation and Inhibits c-Myc Activity

FBXO32 (MAFbx/Atrogin-1) is an E3 ubiquitin ligase that is markedly up-regulated in muscle atrophy. Although some data indicate that FBXO32 may play an important role in tumorigenesis, the molecular mechanism of FBXO32 in tumorigenesis has been poorly understood. Here, we present evidence that FBXO3...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Mei, Zhichao, Zhang, Dawei, Hu, Bo, Wang, Jing, Shen, Xian, Xiao, Wuhan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481220/
https://ncbi.nlm.nih.gov/pubmed/25944903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645978
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