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Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate()
SARS main protease is essential for life cycle of SARS coronavirus and may be a key target for developing anti-SARS drugs. Recently, the enzyme expressed in Escherichia coli was characterized using a HPLC assay to monitor the formation of products from 11 peptide substrates covering the cleavage sit...
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| Publicat a: | Biochem Biophys Res Commun |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier Inc.
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7134607/ https://ncbi.nlm.nih.gov/pubmed/15147951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2004.04.098 |
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