Kinetic Characterization and Inhibitor Screening for the Proteases Leading to Identification of Drugs against SARS-CoV-2

Coronavirus (CoV) disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has claimed many lives worldwide and is still spreading since December 2019. The 3C-like protease (3CL(pro)) and papain-like protease (PL(pro)) are essential for maturation of viral...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Kuo, Chih-Jung, Chao, Tai-Ling, Kao, Han-Chieh, Tsai, Ya-Min, Liu, Yi-Kai, Wang, Lily Hui-Ching, Hsieh, Ming-Chang, Chang, Sui-Yuan, Liang, Po-Huang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2021
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097444/
https://ncbi.nlm.nih.gov/pubmed/33526482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02577-20
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