Discovery of M Protease Inhibitors Encoded by SARS-CoV-2

The coronavirus (CoV) disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome CoV-2 (SARS-CoV-2) is a health threat worldwide. Viral main protease (M(pro), also called 3C‐like protease [3CL(pro)]) is a therapeutic target for drug discovery. Herein, we report that GC376, a broad-...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Hung, Hui-Chen, Ke, Yi-Yu, Huang, Sheng Yu, Huang, Peng-Nien, Kung, Yu-An, Chang, Teng-Yuan, Yen, Kuei-Jung, Peng, Tzu-Ting, Chang, Shao-En, Huang, Chin-Ting, Tsai, Ya-Ru, Wu, Szu-Huei, Lee, Shiow-Ju, Lin, Jiunn-Horng, Liu, Bing-Sin, Sung, Wang-Chou, Shih, Shin-Ru, Chen, Chiung-Tong, Hsu, John Tsu-An
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449189/
https://ncbi.nlm.nih.gov/pubmed/32669265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00872-20
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