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Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate()

SARS main protease is essential for life cycle of SARS coronavirus and may be a key target for developing anti-SARS drugs. Recently, the enzyme expressed in Escherichia coli was characterized using a HPLC assay to monitor the formation of products from 11 peptide substrates covering the cleavage sit...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Kuo, Chih-Jung, Chi, Ya-Hui, Hsu, John T.-A, Liang, Po-Huang
Format: Artigo
Language:Inglês
Published: Elsevier Inc. 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7134607/
https://ncbi.nlm.nih.gov/pubmed/15147951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2004.04.098
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