Human RAP1 specifically protects telomeres of senescent cells from DNA damage

Repressor/activator protein 1 (RAP1) is a highly evolutionarily conserved protein found at telomeres. Although yeast Rap1 is a key telomere capping protein preventing non‐homologous end joining (NHEJ) and consequently telomere fusions, its role at mammalian telomeres in vivo is still controversial....

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Dades bibliogràfiques
Publicat a:EMBO Rep
Autors principals: Lototska, Liudmyla, Yue, Jia‐Xing, Li, Jing, Giraud‐Panis, Marie‐Josèphe, Songyang, Zhou, Royle, Nicola J, Liti, Gianni, Ye, Jing, Gilson, Eric, Mendez‐Bermudez, Aaron
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132343/
https://ncbi.nlm.nih.gov/pubmed/32096305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949076
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