244: Homologous 2′,5′-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity

Efficient and productive virus infection often requires viral countermeasures that block innate immunity. The interferon-inducible 2′,5-oligoadenylate (2-5A) synthetases (OAS) and ribonuclease L (RNase L) are components of a potent host antiviral pathway. We previously showed that murine coronavirus...

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Gepubliceerd in:Cytokine
Hoofdauteurs: Silverman, Robert H., Zhang, Rong, Jha, Babal K., Ogden, Kristen M., Dong, Beihua, Elliott, Ruth, Zhao, Ling, Patton, John T., Weiss, Susan R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Published by Elsevier Ltd. 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7129772/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2013.06.247
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