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PKR inhibitors suppress endoplasmic reticulum stress and subdue glucolipotoxicity-mediated impairment of insulin secretion in pancreatic beta cells

Type 2 diabetes mellitus is characterized by insulin resistance and hypersecretion of insulin from the pancreas to compensate for decreased insulin sensitivity in the peripheral tissues. In later stages of the disease insulin-secreting beta cell degeneration commences and patients require insulin re...

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Detalhes bibliográficos
Publicado no:Turk J Biol
Main Authors: YALÇIN, Abdullah, ŞARKICI, Gülçin, KOLAÇ, Umut Kerem
Formato: Artigo
Idioma:Inglês
Publicado em: The Scientific and Technological Research Council of Turkey 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7129068/
https://ncbi.nlm.nih.gov/pubmed/32256145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3906/biy-1909-20
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