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Glucolipotoxicity of the pancreatic beta-cell: Myth or reality?

The glucolipotoxicity hypothesis postulates that chronically elevated levels of glucose and fatty acids adversely affect pancreatic beta-cell function and thereby contribute to the deterioration of insulin secretion in type 2 diabetes. Whereas ample experimental evidence in in vitro systems support...

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Bibliografske podrobnosti
Glavni avtor: Poitout, Vincent
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889238/
https://ncbi.nlm.nih.gov/pubmed/18793158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0360901
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