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PROTEOMICS ANALYSIS OF ROUGH ENDOPLASMIC RETICULUM IN PANCREATIC BETA CELLS

Pancreatic beta cells have well-developed endoplasmic reticulum (ER) to accommodate for the massive production and secretion of insulin. ER homeostasis is vital for normal beta cell function. Perturbation of ER homeostasis contributes to beta cell dysfunction in both type 1 and type 2 diabetes. To s...

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Publicat a:Proteomics
Autors principals: Lee, Jin-sook, Wu, Yanning, Skallos, Patracia, Fang, Jingye, Zhang, Xuebao, Karnovsky, Alla, Woods, James, Stemmer, Paul M., Liu, Ming, Zhang, Kezhong, Chen, Xuequn
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489703/
https://ncbi.nlm.nih.gov/pubmed/25546123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400345
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