PROTEOMICS ANALYSIS OF ROUGH ENDOPLASMIC RETICULUM IN PANCREATIC BETA CELLS

Pancreatic beta cells have well-developed endoplasmic reticulum (ER) to accommodate for the massive production and secretion of insulin. ER homeostasis is vital for normal beta cell function. Perturbation of ER homeostasis contributes to beta cell dysfunction in both type 1 and type 2 diabetes. To s...

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Détails bibliographiques
Publié dans:Proteomics
Auteurs principaux: Lee, Jin-sook, Wu, Yanning, Skallos, Patracia, Fang, Jingye, Zhang, Xuebao, Karnovsky, Alla, Woods, James, Stemmer, Paul M., Liu, Ming, Zhang, Kezhong, Chen, Xuequn
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489703/
https://ncbi.nlm.nih.gov/pubmed/25546123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400345
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