PROTEOMICS ANALYSIS OF ROUGH ENDOPLASMIC RETICULUM IN PANCREATIC BETA CELLS

Pancreatic beta cells have well-developed endoplasmic reticulum (ER) to accommodate for the massive production and secretion of insulin. ER homeostasis is vital for normal beta cell function. Perturbation of ER homeostasis contributes to beta cell dysfunction in both type 1 and type 2 diabetes. To s...

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Detalhes bibliográficos
Publicado no:Proteomics
Main Authors: Lee, Jin-sook, Wu, Yanning, Skallos, Patracia, Fang, Jingye, Zhang, Xuebao, Karnovsky, Alla, Woods, James, Stemmer, Paul M., Liu, Ming, Zhang, Kezhong, Chen, Xuequn
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489703/
https://ncbi.nlm.nih.gov/pubmed/25546123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400345
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