PROTEOMICS ANALYSIS OF ROUGH ENDOPLASMIC RETICULUM IN PANCREATIC BETA CELLS

Pancreatic beta cells have well-developed endoplasmic reticulum (ER) to accommodate for the massive production and secretion of insulin. ER homeostasis is vital for normal beta cell function. Perturbation of ER homeostasis contributes to beta cell dysfunction in both type 1 and type 2 diabetes. To s...

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Pubblicato in:Proteomics
Autori principali: Lee, Jin-sook, Wu, Yanning, Skallos, Patracia, Fang, Jingye, Zhang, Xuebao, Karnovsky, Alla, Woods, James, Stemmer, Paul M., Liu, Ming, Zhang, Kezhong, Chen, Xuequn
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489703/
https://ncbi.nlm.nih.gov/pubmed/25546123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400345
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