Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism

Breast cancer is the most common cancer among American women and a major cause of mortality. To identify metabolic pathways as potential targets to treat metastatic breast cancer, we performed metabolomics profiling on breast cancer cell line MDA-MB-231 and its tissue-tropic metastatic subclones. He...

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書誌詳細
出版年:Mol Cancer Res
主要な著者: Li, Albert M., Ducker, Gregory S., Li, Yang, Seoane, Jose A., Xiao, Yiren, Melemenidis, Stavros, Zhou, Yiren, Liu, Ling, Vanharanta, Sakari, Graves, Edward E., Rankin, Erinn B., Curtis, Christina, Massagué, Joan, Rabinowitz, Joshua D., Thompson, Craig B., Ye, Jiangbin
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127984/
https://ncbi.nlm.nih.gov/pubmed/31941752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0606
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