TGFβ and Hippo pathways cooperate to enhance sarcomagenesis and metastasis through the hyaluronan mediated motility receptor (HMMR)

High-grade sarcomas are metastatic and pose a serious threat to patient survival. Undifferentiated pleomorphic sarcoma (UPS) is a particularly dangerous and relatively common sarcoma subtype diagnosed in adults. UPS contain large quantities of extracellular matrix (ECM) including Hyaluronic Acid (HA...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Ye, Shuai, Liu, Ying, Fuller, Ashley M., Katti, Rohan, Ciotti, Gabrielle E., Chor, Susan, Zahidul Alam, Md., Devalaraja, Samir, Lorent, Kristin, Weber, Kristy, Haldar, Malay, Pack, Michael A., Eisinger-Mathason, T.S. Karin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127956/
https://ncbi.nlm.nih.gov/pubmed/31988250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0877
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