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Identification, Design and Synthesis of Tubulin-Derived Peptides as Novel Hyaluronan Mimetic Ligands for the Receptor for Hyaluronan-Mediated Motility (RHAMM/HMMR)

Fragments of the extracellular matrix component hyaluronan (HA) promote tissue inflammation, fibrosis and tumor progression. HA fragments act through HA receptors including CD44, LYVE1, TLR2,4 and the receptor for hyaluronan mediated motility (RHAMM/HMMR). RHAMM is a multifunctional protein with bot...

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Bibliografiske detaljer
Udgivet i:Integr Biol (Camb)
Main Authors: Esguerra, Kenneth V. N., Tolg, Cornelia, Akentieva, Natalia, Price, Matthew, Cho, Choi-Fong, Lewis, John D., McCarthy, James B., Turley, Eva A., Luyt, Leonard G.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721638/
https://ncbi.nlm.nih.gov/pubmed/26456171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ib00222b
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