Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases

In the search for anti-SARS-CoV, tanshinones derived from Salvia miltiorrhiza were found to be specific and selective inhibitors for the SARS-CoV 3CL(pro) and PL(pro), viral cysteine proteases. A literature search for studies involving the seven isolated tanshinone hits showed that at present, none...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Park, Ji-Young, Kim, Jang Hoon, Kim, Young Min, Jeong, Hyung Jae, Kim, Dae Wook, Park, Ki Hun, Kwon, Hyung-Jun, Park, Su-Jin, Lee, Woo Song, Ryu, Young Bae
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127169/
https://ncbi.nlm.nih.gov/pubmed/22884354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.07.038
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