Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava

Phlorotannins have been isolated and are the first of their type showing competitively inhibitory activity toward SARS-CoV 3CLpro. Dieckol showed the most potent SARS-CoV 3CLpro trans/cis-cleavage inhibitory effects with high association rate. [Figure: see text]

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Park, Ji-Young, Kim, Jang Hoon, Kwon, Jung Min, Kwon, Hyung-Jun, Jeong, Hyung Jae, Kim, Young Min, Kim, Doman, Lee, Woo Song, Ryu, Young Bae
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126891/
https://ncbi.nlm.nih.gov/pubmed/23647823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.04.026
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