Geranylated flavonoids displaying SARS-CoV papain-like protease inhibition from the fruits of Paulownia tomentosa

SARS-CoV papain-like protease (PLpro) is an important antiviral target due to its key roles in SARS virus replication. The MeOH extracts of the fruits of the Paulownia tree yielded many small molecules capable of targeting PLpro. Five of these compounds were new geranylated flavonoids, tomentin A, t...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Cho, Jung Keun, Curtis-Long, Marcus J., Lee, Kon Ho, Kim, Dae Wook, Ryu, Hyung Won, Yuk, Heung Joo, Park, Ki Hun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. Published by Elsevier Ltd. 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126831/
https://ncbi.nlm.nih.gov/pubmed/23623680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.03.027
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