Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition

As part of our search for botanical sources of SARS-CoV 3CL(pro) inhibitors, we selected Torreya nucifera, which is traditionally used as a medicinal plant in Asia. The ethanol extract of T. nucifera leaves exhibited good SARS-CoV 3CL(pro) inhibitory activity (62% at 100 μg/mL). Following bioactivit...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Ryu, Young Bae, Jeong, Hyung Jae, Kim, Jang Hoon, Kim, Young Min, Park, Ji-Young, Kim, Doman, Naguyen, Thi Thanh Hanh, Park, Su-Jin, Chang, Jong Sun, Park, Ki Hun, Rho, Mun-Chual, Lee, Woo Song
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126309/
https://ncbi.nlm.nih.gov/pubmed/20934345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.09.035
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