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Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding

The crystal structure of griffithsin, an antiviral lectin from the red alga Griffithsia sp., was solved and refined at 1.3 Å resolution for the free protein and 0.94 Å for a complex with mannose. Griffithsin molecules form a domain-swapped dimer, in which two β strands of one molecule complete a β p...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Ziółkowska, Natasza E., O'Keefe, Barry R., Mori, Toshiyuki, Zhu, Charles, Giomarelli, Barbara, Vojdani, Fakhrieh, Palmer, Kenneth E., McMahon, James B., Wlodawer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126681/
https://ncbi.nlm.nih.gov/pubmed/16843894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2006.05.017
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