Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin

The mode of binding of oligosaccharides to griffithsin, an antiviral lectin from the red alga Griffithsia sp., was investigated by a combination of X‐ray crystallography, isothermal titration calorimetry, and molecular modeling. The structures of complexes of griffithsin with 1→6α‐mannobiose and wit...

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Vydáno v:Proteins
Hlavní autoři: Ziółkowska, Natasza E., Shenoy, Shilpa R., O'Keefe, Barry R., McMahon, James B., Palmer, Kenneth E., Dwek, Raymond A., Wormald, Mark R., Wlodawer, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2007
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167611/
https://ncbi.nlm.nih.gov/pubmed/17340634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21336
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