Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin

The mode of binding of oligosaccharides to griffithsin, an antiviral lectin from the red alga Griffithsia sp., was investigated by a combination of X‐ray crystallography, isothermal titration calorimetry, and molecular modeling. The structures of complexes of griffithsin with 1→6α‐mannobiose and wit...

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Bibliografiske detaljer
Udgivet i:Proteins
Main Authors: Ziółkowska, Natasza E., Shenoy, Shilpa R., O'Keefe, Barry R., McMahon, James B., Palmer, Kenneth E., Dwek, Raymond A., Wormald, Mark R., Wlodawer, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Subscription Services, Inc., A Wiley Company 2007
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167611/
https://ncbi.nlm.nih.gov/pubmed/17340634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21336
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