Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin

The mode of binding of oligosaccharides to griffithsin, an antiviral lectin from the red alga Griffithsia sp., was investigated by a combination of X‐ray crystallography, isothermal titration calorimetry, and molecular modeling. The structures of complexes of griffithsin with 1→6α‐mannobiose and wit...

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Publicado en:Proteins
Autores principales: Ziółkowska, Natasza E., Shenoy, Shilpa R., O'Keefe, Barry R., McMahon, James B., Palmer, Kenneth E., Dwek, Raymond A., Wormald, Mark R., Wlodawer, Alexander
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2007
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167611/
https://ncbi.nlm.nih.gov/pubmed/17340634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21336
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