Activity of and Effect of Subcutaneous Treatment with the Broad-Spectrum Antiviral Lectin Griffithsin in Two Laboratory Rodent Models

Griffithsin (GRFT) is a red-alga-derived lectin that binds the terminal mannose residues of N-linked glycans found on the surface of human immunodeficiency virus type 1 (HIV-1), HIV-2, and other enveloped viruses, including hepatitis C virus (HCV), severe acute respiratory syndrome coronavirus (SARS...

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Main Authors: Barton, Christopher, Kouokam, J. Calvin, Lasnik, Amanda B., Foreman, Oded, Cambon, Alexander, Brock, Guy, Montefiori, David C., Vojdani, Fakhrieh, McCormick, Alison A., O'Keefe, Barry R., Palmer, Kenneth E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910741/
https://ncbi.nlm.nih.gov/pubmed/24145548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01407-13
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