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Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs
The importance of phosphonoamidate prodrugs (ProTides) of acyclic nucleoside phosphonate (ANPs) is highlighted by the approval of Tenofovir Alafenamide Fumarate for the treatment of HIV and HBV infections. In the present paper we are reporting an expedient, one-pot, two-steps synthesis of allyl phos...
Shranjeno v:
| izdano v: | Bioorg Med Chem |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier Ltd.
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7126595/ https://ncbi.nlm.nih.gov/pubmed/29880251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.05.034 |
| Oznake: |
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