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Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs
The importance of phosphonoamidate prodrugs (ProTides) of acyclic nucleoside phosphonate (ANPs) is highlighted by the approval of Tenofovir Alafenamide Fumarate for the treatment of HIV and HBV infections. In the present paper we are reporting an expedient, one-pot, two-steps synthesis of allyl phos...
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| 出版年: | Bioorg Med Chem |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier Ltd.
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7126595/ https://ncbi.nlm.nih.gov/pubmed/29880251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.05.034 |
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