The impact of patient characteristics on enzalutamide pharmacokinetics and how this relates to treatment toxicity and efficacy in metastatic prostate cancer patients

PURPOSE: The aim of the study is to investigate the influence of patient characteristics, age and body mass index (BMI), on pharmacokinetics of enzalutamide, and to study the relationships between drug exposure and enzalutamide efficacy and toxicity, in mCRPC patients. METHODS: Data were collected i...

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Vydáno v:Cancer Chemother Pharmacol
Hlavní autoři: Benoist, Guillemette E., van Oort, Inge M., Burger, David M., Mehra, Niven, van Erp, Nielka P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2020
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125069/
https://ncbi.nlm.nih.gov/pubmed/32076807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04039-7
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