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The impact of patient characteristics on enzalutamide pharmacokinetics and how this relates to treatment toxicity and efficacy in metastatic prostate cancer patients

PURPOSE: The aim of the study is to investigate the influence of patient characteristics, age and body mass index (BMI), on pharmacokinetics of enzalutamide, and to study the relationships between drug exposure and enzalutamide efficacy and toxicity, in mCRPC patients. METHODS: Data were collected i...

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Detaylı Bibliyografya
Yayımlandı:Cancer Chemother Pharmacol
Asıl Yazarlar: Benoist, Guillemette E., van Oort, Inge M., Burger, David M., Mehra, Niven, van Erp, Nielka P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125069/
https://ncbi.nlm.nih.gov/pubmed/32076807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04039-7
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