Pharmacokinetic Aspects of the Two Novel Oral Drugs Used for Metastatic Castration-Resistant Prostate Cancer: Abiraterone Acetate and Enzalutamide

Two novel oral drugs that target androgen signaling have recently become available for the treatment of metastatic castration-resistant prostate cancer (mCRPC). Abiraterone acetate inhibits the synthesis of the natural ligands of the androgen receptor, whereas enzalutamide directly inhibits the andr...

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Udgivet i:Clin Pharmacokinet
Main Authors: Benoist, Guillemette E., Hendriks, Rianne J., Mulders, Peter F. A., Gerritsen, Winald R., Somford, Diederik M., Schalken, Jack A., van Oort, Inge M., Burger, David M., van Erp, Nielka P.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2016
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069300/
https://ncbi.nlm.nih.gov/pubmed/27106175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-016-0403-6
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