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The impact of patient characteristics on enzalutamide pharmacokinetics and how this relates to treatment toxicity and efficacy in metastatic prostate cancer patients

PURPOSE: The aim of the study is to investigate the influence of patient characteristics, age and body mass index (BMI), on pharmacokinetics of enzalutamide, and to study the relationships between drug exposure and enzalutamide efficacy and toxicity, in mCRPC patients. METHODS: Data were collected i...

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Опубликовано в: :Cancer Chemother Pharmacol
Главные авторы: Benoist, Guillemette E., van Oort, Inge M., Burger, David M., Mehra, Niven, van Erp, Nielka P.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125069/
https://ncbi.nlm.nih.gov/pubmed/32076807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04039-7
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